Journal: International Journal of Medical Sciences
Article Title: Quantitative DNA Methylation Analysis and Epigenotype-Phenotype Correlations in Taiwanese Patients with Silver-Russell Syndrome
doi: 10.7150/ijms.84154
Figure Lengend Snippet: The relationships between IC1 methylation level by the MassARRAY assay and z scores of birth weight, birth height, and birth head circumference (HC) in the Silver-Russell syndrome subjects with IC1 hypomethylation. (A) Birth weight z score (n = 28, r = 0.184, p > 0.05). (B) Birth height z score (n = 22, r = 0.184, p > 0.05). (C) Birth HC z score (n = 19, r = -0.416, p > 0.05). IC, imprinting center.
Article Snippet: All diagnostic examinations were performed by methylation profiling of H19 -associated IC1 and the imprinted PEG1/MEST region using MS-HRM and high-resolution quantitative methylation profiling with a methylation-specific PCR assay using the MassARRAY EpiTYPER platform (Sequenom, San Diego, CA, USA).
Techniques: Methylation